I think that is normally wise advice that I would give myself, but Brexit, like many other "culture war" issues, was pretty finely balanced, and moderates should try to corral those on the extremes of their position as much as they can to avoid doing damage.
Personally I find ignoring them is the best policy.
Example a rather right wing professor in University College Dublin who is anti-vaccine and anti-every other public health measure put herself forward as a candidate in a recent Irish parliamentary by-election. She wasn't allowed into the election count as she refused to wear a mask. She then proceeded to berate the Garda sergeant on duty at the count, live-streaming the events, and claimed blue bloody murder, whilst at one point claiming that she had more social media followers than all the "mainstream" Irish political parties put together.
She ended up with 169 votes (plus the Garda sergeant (who had the patience of Job and is due a medal for putting up with her) observed that she didn't have as many followers though as David Beckham!).
My point being is that the extremes on Twitter are best left ignored because they aren't the views of the majority of reasonable people. Giving them the oxygen of publicity just eggs them on more.
Incidentally, I do say that as someone who does not like seeing my own national flag, the Irish tricolour, being paraded around by terrorists, former terrorists, or any political party (the extreme right are using it here too) for their own political purposes. It is something to respect.