The flyover is indeed 50.
In the early days IETs (as they then were) were intended to be used on King’s Lynn services, indeed gauge clearance was planned up to Lynn. However when it was realised what a pain they’d be for power, and dwell time at Cambridge, for essentially no benefit (and lots of cost), the plan was changed before they were ordered.
And, of course, the door layout is not conducive to peak calls at Letchworth and Royston either; nor for places like Waterbeach and the masses of cycles we used to get on Cambridge stuff.
To use a 377/379 (insert other 100mph commuter-based unit) over an 80x, the effective loss of speed is as follows:
Northbound - Oakleigh Park to Woolmer Green, 15mph loss, 15 miles, one minute. Woolmer Green to Hitchin, 25mph loss, 8 or so miles (braking neglected for the junctions), about 1 minute. Hardly a major gain when you have loads of other 100mph units running about too.
Southbound - Hitchin to Welwyn North Tunnel, 25mph loss, 8 miles, one minute. Welwyn North Tunnel to Welwyn North station, 5mph loss, 1 mile, no loss (realistically). Welwyn North station to Potters Bar, 15mph loss, 10 miles. Less than one minute loss.
It's better to just operate a timetable planned for 100mph between Wood Green and Hitchin, with Intercity units having a small engineering allowance plugged in.