However on that theme, if you are driving over those summits is there any noticeable engine performance downgrade as you are over 1000' and therefore lower air pressure?
Going from 0 to +1000ft is only about a 3% decrease in air density/pressure, and turbocharging (which most rail diesel engines have) offsets a lot of the effect of that.
But a 1000ft rail summit isn't that high in world terms - e.g. there's a good few mainlines in the US that have 3000 to 6000+ foot summits (the now-mothballed
Tennessee Pass line in Colorado has a 10221ft summit, the highest mainline in North America). China has the
highest altitude mainline in the world at over 16000ft (which was diesel operated when opened).
Probably the biggest problem with operating powerful diesel trains in the mountains is dealing with exhaust gas clearance in very long tunnels, often involving doors at one end of a tunnel and powerful fans to push fresh air in and exhaust gasses out when the doors are closed (after a train has passed through). If the train has multiple locos, the exhaust from the leading locos fills the tunnel so the trailing loco diesel engines are using air with reduced oxygen content, resulting in inefficient/incomplete combustion (and black smoke pouring out of the high end of the tunnel when a train emerges).