I'm no rolling stock engineer, nor am I an aircraft engineer, but do aircraft really have welded double skin extruded aluminium fuselages, and are those fuselages really designed with the structural rigidity and torsional stiffness needed to safely tilt repeatedly for 30+ years ?
I would point out one of the principle reasons the Grayrigg derailment was survivable for many passengers was not solely down to the strength of the bodyshell, there was also an element of extreme good luck with the way the Pendolino struck the trackside OLE masts. The masts were demolished, as one would expect, but fortunately didn't penetrate any of the vehicles. The forces involved were so significant the concrete mast foundations were pulled clean out of the ground and several bogies then impacted those foundations.
That is in stark contrast to Hatfield, where a Mark 4 RSB vehicle, after derailing, hit and demolished two OLE masts (both taller headspan masts). The masts were removed from their foundations and as they were being ripped from their foundations, entered the vehicle, caused significant damage internally and ripped the roof and parts of the bodysides off down to lower window frame level. It was in this vehicle all of the fatalities occurred.
I know the Pendolino stock is very well built, but it wouldn't have fared any differently had luck been even more against the railway that day at Grayrigg.