While not in any way a valid test, I have used Train Simulator to drive Bristol to Exeter and done it at 125mph where it's relatively smooth/straight. I only managed to save about 5 minutes from Bristol to Taunton compared to a 30 minute journey time, which is fairly straight almost all the way. However from there to Exeter it was not possible to get to 125mph easily, and certainly not sustain it, as crossing the Blackdown Hills area and navigating the lower Exe valley sees much more curvature. I get the impression Taunton-Tiverton, which is 100mph, has been absolutely maxed out and could be among the steepest 100mph curves in the country.
The Reading-Taunton line of course has the big obstacle of following the Kennet & Avon canal through much of its eastern half, which leads to some very tight curves between Kintbury and Pewsey. The only way 125mph or anything above 100 is happening there is if the line was redrawn and straightened, which will obviously not happen. Over the Somerset levels is straighter, but then presumably ground conditions are not so good.