Hunts Cross can be accessed with one change from London at Manchester Piccadilly. Same for Liverpool South Parkway although in this case the change can also be made at Runcorn or Lime Street. I forgot LSP no longer has a direct train to London since the LNWR Liverpool - London service was split.Anywhere on Merseyrail Northern Line would entail two changes, unless similarly Central to Lime Street counted as a single interchange (which it isn't really, though not too far to walk), or unless/until London trains stopped at South Parkway.
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